Publications

Erdmann EA, Forbes M,Becker M, Perez S, Hundley HA (2024) ADR-2 regulates fertility and oocyte fate in C. elegans. GENETICS, in press.

Eliad B, Schneider N, Ben-Naim Zgayer O, Amichan Y, Glaser F, Erdmann EA, Rajendren S, Hundley HA and Lamm AT (2024) ADBP-1 regulates ADR-2 nuclear localization to control editing substrate selection. NAR, in press

Dhakal A, Salim C, Skelly M, Amichan Y, Lamm AT and Hundley HA (2024) ADARs regulate cuticle collagen expression and promote organismal survival to pathogen infection. BMC Biology, 2024 Feb 16;22(1):37. PDF

Mahapatra A, Dhakal A, Noguchi A, Vadlamani P and Hundley HA (2023) ADAR-mediated regulationof PQM-1 expression in neurons impacts gene expression throughout C. elegans and regulates survival from hypoxia. PLOS Biology, 2023 Sep 25;21(9):e3002150. PDF

Raghava Kurup R, Oakes EK, Vadlamani P, Nwosu O, Danthi P and Hundley HA (2022) ADAR3 activates NF-kB signaling and promotes glioblastoma cell resistance to temozolomide, Scientific Reports, 2022 Aug 3;12(1):13362. doi: 10.1038/s41598-022-17559-4. PDF

Raghava Kurup R, Oakes EK, Manning AC, Mukherjee P, Vadlamani P and Hundley HA (2022) RNA binding by ADAR3 inhibits adenosine-to-inosine editing and promotes expression of the immune response protein MAVS, JBC, 2022 Jul 15;102267. doi: 10.1016/j.jbc.2022.102267. PDF

Erdmann EA, Abraham O and Hundley HA (2022) Caenorhabditis elegans expressing a Vitellogenin::GFP fusion protein show reduced embryo content and brood size, Micropublication Biology, 2022Mar 1;2022:10.17912/micropub.biology.000532.

Mukherjee P*, Raghava Kurup R* and Hundley HA (2021) RNA immunoprecipitation to find targets of RNA modification enzymes, Methods in Enzymology: RNA Modification Enzymes, 2021;658:137-160.

Erdmann EA, Mahapatra A, Mukherjee P, Yang B and Hundley HA (2021) To protect and modify double-stranded RNA – the critical roles of ADARs in development, immunity and oncogenesis. Critical Reviews in Biochemistry and Molecular Biology, 2021 Feb; 56(1):54-87. PDF

Rajendren S, Dhakal A, Vadlamani P, Townsend J, Deffit SN and Hundley HA (2021) Profiling neural editomes reveals a molecular mechanism to regulate RNA editing during development. Genome Research, 2021 Jan;31(1):27-39. PDF

Arribere JA, Kuroyanagi H and Hundley HA (2020) mRNA editing, processing and quality control in Caenorhabditis elegans, Genetics, 2020 Jul;215(3):531-568. PDF

Ganem NS, Ben-Asher N, Manning AC, Deffit SN, Washburn MC, Wheeler EC, Yeo GW, Zgayer O B-N, Mantsur E, Hundley HA, Lamm AT (2019) Disruption in A-to-I editing levels affects C. elegans development more than a complete lack of editing, Cell Reports, 2019 Apr 23;27(4):1244-1253.

Oshiro RT, Rajendren S, Hundley HA, Kearns DB (2019) Robust Stoichiometry of FliW-CsrA Governs Flagellin Homeostasis and Cytoplasmic Organization in Bacillus subtilis, mBio, 2019 May 21;10(3).

Rajendren S, Manning AC, Al-Awadi H, Yamada K, Takagi Y, Hundley HA (2018) A Protein-Protein Interaction Underlies the Molecular Basis for Substrate Recognition by an Adenosine to Inosine RNA Editing Enzyme, NAR, 2018 Oct 12;46(18):9647-9659.

Deffit SN, Yee BA, Manning AC, Rajendren S, Vadlamani P, Manning AC, Wheeler EC, Domissy A, Washburn, MC, Yeo GW, Hundley HA (2017) The C. elegans neural editome reveals an ADAR target mRNA required for proper chemotaxis, eLife, 2017 Sep 19;6. pii: e28625. doi: 10.7554/eLife.28625.

Oakes E, Vadlamani and Hundley HA (2017) Methods for the Detection of Adenosine-to-Inosine Editing Events in Cellular RNA, Methods in Molecular Biology, volume 1648: mRNA Processing, 2017;103-127. doi: 10.1007/978-1-4939-7204-3_9.

Oakes E, Anderson, Cohen-Gadol A, Hundley HA (2017) Adenosine Deaminase that Acts on RNA 3 (ADAR3) Binding to Glutamate Receptor Subunit B Pre-mRNA Inhibits RNA Editing in Glioblastoma, JBC, 2017 Mar 10; 292(10):4326-4335.

Washburn MC and Hundley HA (2016) Trans and cis factors affecting A-to-I RNA editing efficiency of a noncoding editing target in C. elegans, RNA, 2016 Feb 25.

Deffit SN and Hundley HA (2016) To edit or not to edit: Regulation of ADAR editing specificity and efficiency, WIREs RNA, Jan-Feb;7(1):113-27. doi:10.1002/wrna.1319.

• One of the top 10 Accessed Articles in WIREs RNA for 2016

Washburn MC and Hundley HA (2016) Controlling the editor: the many roles of RNA binding proteins in regulating A-to-I RNA editing, Advances in Experimental Medicine and Biology, volume 907: RNA Processing, 2016;907:189-213. doi:10.1007/978-3-319-29073-7_8.

Wheeler EC, Washburn MC, Major F, Rusch DB, Hundley HA (2015) Noncoding regions of C. elegans mRNA undergo selective adenosine to inosine deamination and contain a small number of editing sites per transcript, RNA Biology, 2015 Feb;12(2):162-74. doi:10.1080/15476286.2015.1017220.

Washburn MC, Kakaradov B, Sundararaman B, Wheeler E, Hoon S, Yeo GW, and Hundley HA (2014) The dsRBP and inactive editor, ADR-1, utilizes dsRNA binding to regulate A-to-I RNA editing across the C. elegans transcriptome, Cell Reports, Feb 27;6(4):599-607.

• IU Press Release: http://news.indiana.edu/releases/iu/2014/02/hundley-messenger-rna.shtml
• Featured on the NSF website News from the Field: http://www.nsf.gov/news/news_summ.jsp?cntn_id=130446&org=NSF&from=news

Hundley HA (2013) Regulation of gene expression through inosine-containing UTRs, In RNA Editing: Current Research and Future Trends, S. Maas, ed. (Horizon Press)

Bass B, Hundley H, Li JB, Peng Z, Pickrell J, Xiao XG, Yang L. (2012) The difficult calls in RNA editing, Nature Biotechnology, Dec 7;30(12):1207-9.

Capshew CR, Dusenbury KL and Hundley HA (2012) Inverted Alu dsRNA structures do not affect localization but alter translation of human mRNAs independent of RNA editing, Nucleic Acids Research (NAR), 2012 Sep 1;40(17):8637-45.

Hundley HA and Bass BL (2010) RNA editing in double-stranded UTRs and other noncoding RNA sequences, TiBS, 2010 Jul;35(7):377-83.